De-escalation of empiric antibiotic therapy in sepsis - an indian observational study
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چکیده
منابع مشابه
De-escalation of empiric antibiotic therapy in sepsis - an indian observational study
Methods We carried out a prospective observational study enrolling patients admitted to the ICU with sepsis from 01/02/2014 to 01/03/2015. Both the medical and surgical units of the ICU were included. “No change” was defined as when empiric therapy was maintained without modification, “Escalation of therapy” was defined when there’s a switch to or addition of an antibiotic with a broader spectr...
متن کاملDe-escalation, adequacy of antibiotic therapy and culture positivity in septic patients: an observational study
OBJECTIVE To evaluate the prevalence of antibiotic de-escalation in patients diagnosed with severe sepsis or septic shock at a public academic tertiary hospital and to evaluate antibiotic adequacy and culture positivity. METHODS The prevalence of antibiotic de-escalation, the adequacy of antibiotic treatment and the rates of culture positivity were analyzed in patients with severe sepsis and ...
متن کاملAntibiotic De-escalation Therapy in Neurosurgical Patients with Ventilator-Associated Pneumonia in Intensive Care Unit: A Retrospective Observational Study
Context: Antibiotic de-escalation practice is gaining interest in the intensive care units (ICU). However, there is limited evidence to support this approach in neurosurgical patients with Ventilator-Associated Pneumonia (VAP) in ICU. Aims: This study examined the practice of antibiotic de-escalation in neurosurgical patients with VAP in ICU and its impact on mortality. Settings and Design: Ret...
متن کاملAntibiotic De-escalation in the Intensive Therapy Unit- a Review
An antibiotic may be defined as a substance or compound that kills or inhibits the growth of, bacteria. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa, viruses. Antibiotic de-escalation is a mechanism whereby the provision of effective initial antibiotic treatment is achieved while avoiding unne...
متن کاملFrequency of empiric antibiotic de-escalation in an acute care hospital with an established Antimicrobial Stewardship Program
BACKGROUND Expanding antimicrobial resistance patterns in the face of stagnant growth in novel antibiotic production underscores the importance of antibiotic stewardship in which de-escalation remains an integral component. We measured the frequency of antibiotic de-escalation in a tertiary care medical center with an established antimicrobial stewardship program to provide a plausible benchmar...
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ژورنال
عنوان ژورنال: Intensive Care Medicine Experimental
سال: 2015
ISSN: 2197-425X
DOI: 10.1186/2197-425x-3-s1-a405